General Information of the Compound
| Compound ID |
CP0841521
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl)pyrido[3,4-b]pyrazin-8-amine
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C22H20N4O3
|
||||||||||||||||||
| Molecular Weight |
388.427
|
||||||||||||||||||
| Canonical SMILES |
COc1ccc(-c2cnc3cncc(Nc4cc(OC)ccc4OC)c3n2)cc1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C22H20N4O3/c1-27-15-6-4-14(5-7-15)18-13-24-19-11-23-12-20(22(19)26-18)25-17-10-16(28-2)8-9-21(17)29-3/h4-13,25H,1-3H3
Show/Hide
|
||||||||||||||||||
| InChIKey |
UOJSYTFKPYHYHF-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT01066, Tyrosine-protein kinase Yes
Protein ID: PT00864, Vascular endothelial growth factor receptor 2