General Information of the Compound
Compound ID
CP0800593
Compound Name
3-((1H-Imidazol-1-yl)methyl)-N-((2S,3S)-1-(2-(butylsulfonyl)hydrazinyl)-3-methyl-1-oxopentan-2-yl)benzamide
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Structure
Formula
C21H31N5O4S
Molecular Weight
449.577
Canonical SMILES
CCCCS(=O)(=O)NNC(=O)[C@@H](NC(=O)c1cccc(Cn2ccnc2)c1)[C@@H](C)CC
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InChI
InChI=1S/C21H31N5O4S/c1-4-6-12-31(29,30)25-24-21(28)19(16(3)5-2)23-20(27)18-9-7-8-17(13-18)14-26-11-10-22-15-26/h7-11,13,15-16,19,25H,4-6,12,14H2,1-3H3,(H,23,27)(H,24,28)/t16-,19-/m0/s1
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InChIKey
MPTLROKYVNNKPD-LPHOPBHVSA-N
Physicochemical Property
logP
1.8266
Rotatable Bonds
12
Heavy Atom Count
31
Polar Areas
122.19
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 73213255
ChEMBL ID
CHEMBL3105384
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01553, Type-2 angiotensin II receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 100000 nM
   TI
   LI
   LO
   TS