General Information of the Compound
Compound ID
CP0795364
Compound Name
Trifluoro-acetate(2R,3R)-8-trifluoromethoxy-3-(2,4,5-trifluoro-phenyl)-1,2,3,4-tetrahydro-benzo[4,5]imidazo[1,2-a]pyridin-2-yl-ammonium
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Structure
Formula
C20H14F9N3O3
Molecular Weight
515.332
Canonical SMILES
N[C@H]1Cn2c(nc3ccc(OC(F)(F)F)cc32)C[C@@H]1c1cc(F)c(F)cc1F.O=C(O)C(F)(F)F
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InChI
InChI=1S/C18H13F6N3O.C2HF3O2/c19-11-6-13(21)12(20)4-9(11)10-5-17-26-15-2-1-8(28-18(22,23)24)3-16(15)27(17)7-14(10)25;3-2(4,5)1(6)7/h1-4,6,10,14H,5,7,25H2;(H,6,7)/t10-,14+;/m1./s1
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InChIKey
DSLBJZBRQKQEFC-LOSLGVLSSA-N
Physicochemical Property
logP
4.6527
Rotatable Bonds
2
Heavy Atom Count
35
Polar Areas
90.37
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49797610
ChEMBL ID
CHEMBL563155
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 22000 nM
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