General Information of the Compound
Compound ID
CP0761865
Compound Name
tert-butyl 2-((2S,3S)-2-(3-((1H-imidazol-1-yl)methyl)benzamido)-3-methylpentanoyl)hydrazinecarboxylate
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Structure
Formula
C22H31N5O4
Molecular Weight
429.521
Canonical SMILES
CC[C@H](C)[C@H](NC(=O)c1cccc(Cn2ccnc2)c1)C(=O)NNC(=O)OC(C)(C)C
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InChI
InChI=1S/C22H31N5O4/c1-6-15(2)18(20(29)25-26-21(30)31-22(3,4)5)24-19(28)17-9-7-8-16(12-17)13-27-11-10-23-14-27/h7-12,14-15,18H,6,13H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)/t15-,18-/m0/s1
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InChIKey
DSBZXPLUAJWHLW-YJBOKZPZSA-N
Physicochemical Property
logP
2.6318
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
114.35
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 73213253
ChEMBL ID
CHEMBL3105382
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01553, Type-2 angiotensin II receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 100000 nM
   TI
   LI
   LO
   TS