General Information of the Compound
| Compound ID |
CP0755044
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| Compound Name |
N-(4-(cyclohexylamino)quinazolin-6-yl)acrylamide
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| Structure |
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| Formula |
C17H20N4O
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| Molecular Weight |
296.374
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| Canonical SMILES |
C=CC(=O)Nc1ccc2ncnc(NC3CCCCC3)c2c1
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| InChI |
InChI=1S/C17H20N4O/c1-2-16(22)20-13-8-9-15-14(10-13)17(19-11-18-15)21-12-6-4-3-5-7-12/h2,8-12H,1,3-7H2,(H,20,22)(H,18,19,21)
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| InChIKey |
KIOLWXYZBXHLAS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00922, Epidermal growth factor receptor
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000157 | NCI-H1975 | Homo sapiens (Human) | 1 |
| 1 |
IC50 > 40000 nM
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TI
LI
LO
TS
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