General Information of the Compound
| Compound ID |
CP0747495
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| Compound Name |
2-(4-methoxyphenyl)-N-(4-morpholinophenyl)pyrido[3,4-b]pyrazin-8-amine
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| Structure |
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| Formula |
C24H23N5O2
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| Molecular Weight |
413.481
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| Canonical SMILES |
COc1ccc(-c2cnc3cncc(Nc4ccc(N5CCOCC5)cc4)c3n2)cc1
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| InChI |
InChI=1S/C24H23N5O2/c1-30-20-8-2-17(3-9-20)21-16-26-22-14-25-15-23(24(22)28-21)27-18-4-6-19(7-5-18)29-10-12-31-13-11-29/h2-9,14-16,27H,10-13H2,1H3
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| InChIKey |
IKUXHAZDRPCANL-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT01066, Tyrosine-protein kinase Yes
Protein ID: PT00864, Vascular endothelial growth factor receptor 2