General Information of the Compound
Compound ID
CP0733862
Compound Name
3-((1H-Imidazol-1-yl)methyl)-N-((2S,3S)-1-(2-(mesitylsulfonyl)hydrazinyl)-3-methyl-1-oxopentan-2-yl)benzamide
    Show/Hide
Structure
Formula
C26H33N5O4S
Molecular Weight
511.648
Canonical SMILES
CC[C@H](C)[C@H](NC(=O)c1cccc(Cn2ccnc2)c1)C(=O)NNS(=O)(=O)c1c(C)cc(C)cc1C
    Show/Hide
InChI
InChI=1S/C26H33N5O4S/c1-6-18(3)23(26(33)29-30-36(34,35)24-19(4)12-17(2)13-20(24)5)28-25(32)22-9-7-8-21(14-22)15-31-11-10-27-16-31/h7-14,16,18,23,30H,6,15H2,1-5H3,(H,28,32)(H,29,33)/t18-,23-/m0/s1
    Show/Hide
InChIKey
QCUVYESZBGKXSM-MBSDFSHPSA-N
Physicochemical Property
logP
3.01086
Rotatable Bonds
10
Heavy Atom Count
36
Polar Areas
122.19
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 73213179
ChEMBL ID
CHEMBL3105465
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01553, Type-2 angiotensin II receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 8500 nM
   TI
   LI
   LO
   TS