General Information of the Compound
| Compound ID |
CP0733190
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| Compound Name |
N-(3-(pyridin-4-yl)-1H-indazol-5-yl)ethanesulfonamide
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| Structure |
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| Formula |
C14H14N4O2S
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| Molecular Weight |
302.359
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| Canonical SMILES |
CCS(=O)(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1
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| InChI |
InChI=1S/C14H14N4O2S/c1-2-21(19,20)18-11-3-4-13-12(9-11)14(17-16-13)10-5-7-15-8-6-10/h3-9,18H,2H2,1H3,(H,16,17)
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| InChIKey |
HTPBUYMKFQZQOW-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00850, Mitogen-activated protein kinase 1
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000045 | A-375 | Homo sapiens (Human) | 1 |
| 1 |
IC50 > 30000 nM
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