General Information of the Compound
| Compound ID |
CP0726600
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| Compound Name |
N-(4-Morpholin-4-ylphenyl)-2-phenylpyrido[3,4-b]pyrazin-5-amine
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| Structure |
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| Formula |
C23H21N5O
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| Molecular Weight |
383.455
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| Canonical SMILES |
c1ccc(-c2cnc3c(Nc4ccc(N5CCOCC5)cc4)nccc3n2)cc1
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| InChI |
InChI=1S/C23H21N5O/c1-2-4-17(5-3-1)21-16-25-22-20(27-21)10-11-24-23(22)26-18-6-8-19(9-7-18)28-12-14-29-15-13-28/h1-11,16H,12-15H2,(H,24,26)
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| InChIKey |
UXNGTVMJGBIVEX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT01066, Tyrosine-protein kinase Yes
Protein ID: PT00864, Vascular endothelial growth factor receptor 2