General Information of the Compound
| Compound ID |
CP0726599
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| Compound Name |
N-(3-Chloro-4-fluorophenyl)-3-phenylpyrido[3,4-b]pyrazin-8-amine
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| Structure |
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| Formula |
C19H12ClFN4
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| Molecular Weight |
350.784
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| Canonical SMILES |
Fc1ccc(Nc2cncc3nc(-c4ccccc4)cnc23)cc1Cl
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| InChI |
InChI=1S/C19H12ClFN4/c20-14-8-13(6-7-15(14)21)24-17-9-22-10-18-19(17)23-11-16(25-18)12-4-2-1-3-5-12/h1-11,24H
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| InChIKey |
IUZVIJYTCSDYGR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT01066, Tyrosine-protein kinase Yes
Protein ID: PT00864, Vascular endothelial growth factor receptor 2