General Information of the Compound
| Compound ID |
CP0724873
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| Compound Name |
6-(morpholine-4-carbonyl)-3-phenyl-9H-carbazole-1-carboxamide
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| Structure |
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| Formula |
C24H21N3O3
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| Molecular Weight |
399.45
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| Canonical SMILES |
NC(=O)c1cc(-c2ccccc2)cc2c1[nH]c1ccc(C(=O)N3CCOCC3)cc12
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| InChI |
InChI=1S/C24H21N3O3/c25-23(28)20-14-17(15-4-2-1-3-5-15)13-19-18-12-16(6-7-21(18)26-22(19)20)24(29)27-8-10-30-11-9-27/h1-7,12-14,26H,8-11H2,(H2,25,28)
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| InChIKey |
VBMFXGFCLWKXEL-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01214, Tyrosine-protein kinase JAK2
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000068 | A-549 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 2400 nM
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