General Information of the Compound
Compound ID
CP0724304
Compound Name
trifluoro-acetate(1S,2S)-2-(4-benzenesulfonylamino-phenyl)-2-dimethylcarbamoyl-1-((S)-3-fluoro-pyrrolidine-1-carbonyl)-ethyl-ammonium
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Structure
Formula
C24H28F4N4O6S
Molecular Weight
576.569
Canonical SMILES
CN(C)C(=O)[C@@H](c1ccc(NS(=O)(=O)c2ccccc2)cc1)[C@H](N)C(=O)N1CC[C@H](F)C1.O=C(O)C(F)(F)F
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InChI
InChI=1S/C22H27FN4O4S.C2HF3O2/c1-26(2)21(28)19(20(24)22(29)27-13-12-16(23)14-27)15-8-10-17(11-9-15)25-32(30,31)18-6-4-3-5-7-18;3-2(4,5)1(6)7/h3-11,16,19-20,25H,12-14,24H2,1-2H3;(H,6,7)/t16-,19-,20-;/m0./s1
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InChIKey
DCONMFFSKIZACM-BOKRKPFNSA-N
Physicochemical Property
logP
2.1902
Rotatable Bonds
7
Heavy Atom Count
39
Polar Areas
150.11
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49797344
ChEMBL ID
CHEMBL245772
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 80000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00907, Dipeptidyl peptidase 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 870 nM
   TI
   LI
   LO
   TS