General Information of the Compound
Compound ID
CP0719102
Compound Name
trifluoro-acetate(1S,2S)-2-(4-acetylamino-phenyl)-2-dimethylcarbamoyl-1-((S)-3-fluoro-pyrrolidine-1-carbonyl)-ethyl-ammonium
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Structure
Formula
C20H26F4N4O5
Molecular Weight
478.443
Canonical SMILES
CC(=O)Nc1ccc([C@H](C(=O)N(C)C)[C@H](N)C(=O)N2CC[C@H](F)C2)cc1.O=C(O)C(F)(F)F
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InChI
InChI=1S/C18H25FN4O3.C2HF3O2/c1-11(24)21-14-6-4-12(5-7-14)15(17(25)22(2)3)16(20)18(26)23-9-8-13(19)10-23;3-2(4,5)1(6)7/h4-7,13,15-16H,8-10,20H2,1-3H3,(H,21,24);(H,6,7)/t13-,15-,16-;/m0./s1
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InChIKey
GESQYJAAULOVER-GEUPQXMHSA-N
Physicochemical Property
logP
1.3478
Rotatable Bonds
5
Heavy Atom Count
33
Polar Areas
133.04
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49797349
ChEMBL ID
CHEMBL245970
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00907, Dipeptidyl peptidase 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS