General Information of the Compound
| Compound ID |
CP0718988
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| Compound Name |
6-(morpholine-4-carbonyl)-3-(3-propoxyphenyl)-9H-carbazole-1-carboxamide
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| Structure |
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| Formula |
C27H27N3O4
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| Molecular Weight |
457.53
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| Canonical SMILES |
CCCOc1cccc(-c2cc(C(N)=O)c3[nH]c4ccc(C(=O)N5CCOCC5)cc4c3c2)c1
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| InChI |
InChI=1S/C27H27N3O4/c1-2-10-34-20-5-3-4-17(13-20)19-15-22-21-14-18(27(32)30-8-11-33-12-9-30)6-7-24(21)29-25(22)23(16-19)26(28)31/h3-7,13-16,29H,2,8-12H2,1H3,(H2,28,31)
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| InChIKey |
UEKYUVIQMYQIRA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01214, Tyrosine-protein kinase JAK2
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000068 | A-549 | Homo sapiens (Human) | 1 |
| 1 |
IC50 = 5820 nM
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