General Information of the Compound
Compound ID
CP0714522
Compound Name
(11R,12R)-12-azaniumyl-4-(trifluoromethyl)-11-(2,4,5-trifluorophenyl)-1,5,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8-tetraen-5-ium; bis(2,2,2-trifluoroacetate)
    Show/Hide
Structure
Formula
C21H14F12N4O4
Molecular Weight
614.343
Canonical SMILES
N[C@H]1Cn2c(nc3cnc(C(F)(F)F)cc32)C[C@@H]1c1cc(F)c(F)cc1F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
    Show/Hide
InChI
InChI=1S/C17H12F6N4.2C2HF3O2/c18-9-3-11(20)10(19)1-7(9)8-2-16-26-13-5-25-15(17(21,22)23)4-14(13)27(16)6-12(8)24;2*3-2(4,5)1(6)7/h1,3-5,8,12H,2,6,24H2;2*(H,6,7)/t8-,12+;;/m1../s1
    Show/Hide
InChIKey
IZCQHJKKGJQRIZ-KHEMJLMASA-N
Physicochemical Property
logP
4.8012
Rotatable Bonds
1
Heavy Atom Count
41
Polar Areas
131.33
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 49797602
ChEMBL ID
CHEMBL541438
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS