General Information of the Compound
Compound ID
CP0704347
Compound Name
trifluoro-acetate(1S,2S)-2-dimethylcarbamoyl-1-((S)-3-fluoro-pyrrolidine-1-carbonyl)-2-{4-[methyl-(toluene-4-sulfonyl)-amino]-phenyl}-ethyl-ammonium
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Structure
Formula
C26H32F4N4O6S
Molecular Weight
604.623
Canonical SMILES
Cc1ccc(S(=O)(=O)N(C)c2ccc([C@H](C(=O)N(C)C)[C@H](N)C(=O)N3CC[C@H](F)C3)cc2)cc1.O=C(O)C(F)(F)F
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InChI
InChI=1S/C24H31FN4O4S.C2HF3O2/c1-16-5-11-20(12-6-16)34(32,33)28(4)19-9-7-17(8-10-19)21(23(30)27(2)3)22(26)24(31)29-14-13-18(25)15-29;3-2(4,5)1(6)7/h5-12,18,21-22H,13-15,26H2,1-4H3;(H,6,7)/t18-,21-,22-;/m0./s1
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InChIKey
VWNSRUIIDNVZPN-OVXWWNFRSA-N
Physicochemical Property
logP
2.52292
Rotatable Bonds
7
Heavy Atom Count
41
Polar Areas
141.32
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49797345
ChEMBL ID
CHEMBL429653
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00907, Dipeptidyl peptidase 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS