General Information of the Compound
| Compound ID |
CP0674998
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| Compound Name |
N-(4-Methoxyphenyl)-N'-(3-phenylpyrido[3,4-b]pyrazin-8-yl)urea
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| Structure |
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| Formula |
C21H17N5O2
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| Molecular Weight |
371.4
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| Canonical SMILES |
COc1ccc(NC(=O)Nc2cncc3nc(-c4ccccc4)cnc23)cc1
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| InChI |
InChI=1S/C21H17N5O2/c1-28-16-9-7-15(8-10-16)24-21(27)26-19-12-22-11-18-20(19)23-13-17(25-18)14-5-3-2-4-6-14/h2-13H,1H3,(H2,24,26,27)
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| InChIKey |
GPWYEGZCLUSIDX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT01066, Tyrosine-protein kinase Yes
Protein ID: PT00864, Vascular endothelial growth factor receptor 2