General Information of the Compound
| Compound ID |
CP0674969
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-phenyl-2-(4-(piperidin-1-yl)phenyl)pyrido[3,4-b]pyrazin-8-amine
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C24H23N5
|
||||||||||||||||||
| Molecular Weight |
381.483
|
||||||||||||||||||
| Canonical SMILES |
c1ccc(Nc2cncc3ncc(-c4ccc(N5CCCCC5)cc4)nc23)cc1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H23N5/c1-3-7-19(8-4-1)27-23-16-25-15-22-24(23)28-21(17-26-22)18-9-11-20(12-10-18)29-13-5-2-6-14-29/h1,3-4,7-12,15-17,27H,2,5-6,13-14H2
Show/Hide
|
||||||||||||||||||
| InChIKey |
SZPJDPHRQQQTIT-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT01066, Tyrosine-protein kinase Yes
Protein ID: PT00864, Vascular endothelial growth factor receptor 2