General Information of the Compound
Compound ID
CP0660055
Compound Name
trifluoro-acetate(1S,2S)-2-[4-(acetyl-methyl-amino)-phenyl]-2-dimethylcarbamoyl-1-((S)-3-fluoro-pyrrolidine-1-carbonyl)-ethyl-ammonium
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Structure
Formula
C21H28F4N4O5
Molecular Weight
492.47
Canonical SMILES
CC(=O)N(C)c1ccc([C@H](C(=O)N(C)C)[C@H](N)C(=O)N2CC[C@H](F)C2)cc1.O=C(O)C(F)(F)F
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InChI
InChI=1S/C19H27FN4O3.C2HF3O2/c1-12(25)23(4)15-7-5-13(6-8-15)16(18(26)22(2)3)17(21)19(27)24-10-9-14(20)11-24;3-2(4,5)1(6)7/h5-8,14,16-17H,9-11,21H2,1-4H3;(H,6,7)/t14-,16-,17-;/m0./s1
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InChIKey
DINMLGRFKXWTOX-BDURURIASA-N
Physicochemical Property
logP
1.3721
Rotatable Bonds
5
Heavy Atom Count
34
Polar Areas
124.25
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49797351
ChEMBL ID
CHEMBL246168
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00907, Dipeptidyl peptidase 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS