General Information of the Compound
Compound ID
CP0650853
Compound Name
(7R,8R)-8-(2,4,5-Trifluoro-phenyl)-6,7,8,9-tetrahydro-dipyrido[1,2-a3',4'-d]imidazol-7-ylamine tris hydrochloride
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Structure
Formula
C16H14ClF3N4
Molecular Weight
354.763
Canonical SMILES
Cl.N[C@H]1Cn2c(nc3cnccc32)C[C@@H]1c1cc(F)c(F)cc1F
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InChI
InChI=1S/C16H13F3N4.ClH/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20;/h1-3,5-6,9,13H,4,7,20H2;1H/t9-,13+;/m1./s1
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InChIKey
TZWXUQQRGYTXLS-XVUIFDSFSA-N
Physicochemical Property
logP
2.9376
Rotatable Bonds
1
Heavy Atom Count
24
Polar Areas
56.73
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45270905
ChEMBL ID
CHEMBL552068
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00989, Dipeptidyl peptidase 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS