General Information of the Compound
| Compound ID |
CP0639868
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
(Z)-3-((4-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-N-ethyl-2-oxoindoline-6-carboxamide
Show/Hide
|
||||||||||||||||||
| Formula |
C27H28N4O2
|
||||||||||||||||||
| Molecular Weight |
440.547
|
||||||||||||||||||
| Canonical SMILES |
CCNC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN(C)C)cc1)c1ccccc1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C27H28N4O2/c1-4-28-26(32)20-12-15-22-23(16-20)30-27(33)24(22)25(19-8-6-5-7-9-19)29-21-13-10-18(11-14-21)17-31(2)3/h5-16,29H,4,17H2,1-3H3,(H,28,32)(H,30,33)/b25-24-
Show/Hide
|
||||||||||||||||||
| InChIKey |
YLJGNMFEAJARMT-IZHYLOQSSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01221, TGF-beta receptor type-1
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000150 | HaCaT | Homo sapiens (Human) | 1 |
| 1 |
IC50 > 1000 nM
|
TI
LI
LO
TS
|
|
|---|---|---|---|