General Information of the Compound
| Compound ID |
CP0579230
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-[3-[5-(2-aminopyrimidin-4-yl)-2-piperidin-3-yl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,5-difluorobenzenesulfonamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C24H21F3N6O2S2
|
||||||||||||||||||
| Molecular Weight |
546.6
|
||||||||||||||||||
| Canonical SMILES |
Nc1nccc(n1)-c1sc(nc1-c1cccc(NS(=O)(=O)c2cc(F)ccc2F)c1F)C1CCCNC1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H21F3N6O2S2/c25-14-6-7-16(26)19(11-14)37(34,35)33-17-5-1-4-15(20(17)27)21-22(18-8-10-30-24(28)31-18)36-23(32-21)13-3-2-9-29-12-13/h1,4-8,10-11,13,29,33H,2-3,9,12H2,(H2,28,30,31)
Show/Hide
|
||||||||||||||||||
| InChIKey |
FLSHYSDUYUUQRQ-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound