General Information of the Compound
Compound ID
CP0578375
Compound Name
1-(3-chlorophenyl)sulfonyl-N-[(3S)-oxolan-3-yl]pyrrolo[3,2-c]quinolin-4-amine
    Show/Hide
Structure
Formula
C21H18ClN3O3S
Molecular Weight
427.913
Canonical SMILES
Clc1cccc(c1)S(=O)(=O)n1ccc2c(N[C@H]3CCOC3)nc3ccccc3c12
    Show/Hide
InChI
InChI=1S/C21H18ClN3O3S/c22-14-4-3-5-16(12-14)29(26,27)25-10-8-18-20(25)17-6-1-2-7-19(17)24-21(18)23-15-9-11-28-13-15/h1-8,10,12,15H,9,11,13H2,(H,23,24)/t15-/m0/s1
    Show/Hide
InChIKey
KXYKGHPPJVXDFH-HNNXBMFYSA-N
Physicochemical Property
logP
4.2807
Rotatable Bonds
4
Heavy Atom Count
29
Polar Areas
73.22
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 168283351
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 73 nM
   TI
   LI
   LO
   TS