General Information of the Compound
Compound ID
CP0576031
Compound Name
4-(4-chlorophenyl)-2-[[2-(trifluoromethoxy)benzoyl]amino]thiophene-3-carboxylic acid
    Show/Hide
Structure
Formula
C19H11ClF3NO4S
Molecular Weight
441.814
Canonical SMILES
OC(=O)c1c(NC(=O)c2ccccc2OC(F)(F)F)scc1-c1ccc(Cl)cc1
    Show/Hide
InChI
InChI=1S/C19H11ClF3NO4S/c20-11-7-5-10(6-8-11)13-9-29-17(15(13)18(26)27)24-16(25)12-3-1-2-4-14(12)28-19(21,22)23/h1-9H,(H,24,25)(H,26,27)
    Show/Hide
InChIKey
VXCDOVJCDZMFTR-UHFFFAOYSA-N
Physicochemical Property
logP
5.9176
Rotatable Bonds
5
Heavy Atom Count
29
Polar Areas
75.63
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 168286766
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06716, Anoctamin-1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
IC50 = 5660 nM
   TI
   LI
   LO
   TS