General Information of the Compound
Compound ID
CP0575495
Compound Name
4-(4-chlorophenyl)-2-[(3-methylthiophene-2-carbonyl)amino]thiophene-3-carboxylic acid
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Structure
Formula
C17H12ClNO3S2
Molecular Weight
377.874
Canonical SMILES
Cc1ccsc1C(=O)Nc1scc(c1C(O)=O)-c1ccc(Cl)cc1
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InChI
InChI=1S/C17H12ClNO3S2/c1-9-6-7-23-14(9)15(20)19-16-13(17(21)22)12(8-24-16)10-2-4-11(18)5-3-10/h2-8H,1H3,(H,19,20)(H,21,22)
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InChIKey
XDGOMLARDHIJNO-UHFFFAOYSA-N
Physicochemical Property
logP
5.38892
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
66.4
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 67224690
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06716, Anoctamin-1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
IC50 = 3120 nM
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