General Information of the Compound
Compound ID
CP0574437
Compound Name
4-amino-N-[2-[4-[3-(4-amino-5-chloro-2-methoxyphenyl)-3-oxopropyl]piperidin-1-yl]ethyl]-3,5-dibromobenzenesulfonamide
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Formula
C23H29Br2ClN4O4S
Molecular Weight
652.837
Canonical SMILES
COc1cc(N)c(Cl)cc1C(=O)CCC1CCN(CCNS(=O)(=O)c2cc(Br)c(N)c(Br)c2)CC1
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InChI
InChI=1S/C23H29Br2ClN4O4S/c1-34-22-13-20(27)19(26)12-16(22)21(31)3-2-14-4-7-30(8-5-14)9-6-29-35(32,33)15-10-17(24)23(28)18(25)11-15/h10-14,29H,2-9,27-28H2,1H3
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InChIKey
ANKWCLUOSBVZSG-UHFFFAOYSA-N
Physicochemical Property
logP
4.6914
Rotatable Bonds
10
Heavy Atom Count
35
Polar Areas
127.75
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4799043
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 140 nM
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