General Information of the Compound
Compound ID
CP0567674
Compound Name
2-amino-4-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-4H-benzo[h]chromene-3-carbonitrile
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Structure
Formula
C20H13F5N2OS
Molecular Weight
424.394
Canonical SMILES
NC1=C(C#N)C(c2ccc(cc2)S(F)(F)(F)(F)F)c2ccc3ccccc3c2O1
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InChI
InChI=1S/C20H13F5N2OS/c21-29(22,23,24,25)14-8-5-13(6-9-14)18-16-10-7-12-3-1-2-4-15(12)19(16)28-20(27)17(18)11-26/h1-10,18H,27H2
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InChIKey
CISUNEDRLUOYCJ-UHFFFAOYSA-N
Physicochemical Property
logP
6.71538
Rotatable Bonds
2
Heavy Atom Count
29
Polar Areas
59.04
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155548499
ChEMBL ID
CHEMBL4536562
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT07544, Transcriptional activator Myb
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 3200 nM
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