General Information of the Compound
Compound ID
CP0567554
Compound Name
4-[4-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]butoxy]-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
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Formula
C34H38N4O3S
Molecular Weight
582.77
Canonical SMILES
O=S(=O)(c1ccccc1)n1ccc2c(cccc12)N1CCN(CCCCOc2cccc3C(CCc23)NCC#C)CC1
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InChI
InChI=1S/C34H38N4O3S/c1-2-19-35-31-17-16-29-28(31)12-8-15-34(29)41-26-7-6-20-36-22-24-37(25-23-36)32-13-9-14-33-30(32)18-21-38(33)42(39,40)27-10-4-3-5-11-27/h1,3-5,8-15,18,21,31,35H,6-7,16-17,19-20,22-26H2
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InChIKey
GTFVZIBKTJFULH-UHFFFAOYSA-N
Physicochemical Property
logP
5.0696
Rotatable Bonds
11
Heavy Atom Count
42
Polar Areas
66.81
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4742220
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 50 nM
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