General Information of the Compound
| Compound ID |
CP0565801
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| Compound Name |
N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-7-formyl-6-[1-(oxetan-3-yl)piperidin-4-yl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Formula |
C27H32N6O5
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| Molecular Weight |
520.59
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(C4CCN(CC4)C4COC4)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C27H32N6O5/c1-36-9-10-38-24-12-25(29-14-20(24)13-28)31-27(35)33-6-2-3-19-11-22(23(15-34)30-26(19)33)18-4-7-32(8-5-18)21-16-37-17-21/h11-12,14-15,18,21H,2-10,16-17H2,1H3,(H,29,31,35)
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| InChIKey |
KKMDIRMBOQSJPU-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4