General Information of the Compound
Compound ID
CP0565315
Compound Name
(3S,8S,11S,14S,17S)-11-[(2S)-butan-2-yl]-3-[[(2S)-2,6-diaminohexanoyl]amino]-14-[(4-hydroxyphenyl)methyl]-2,10,13,16-tetraoxo-1,9,12,15-tetrazabicyclo[15.3.0]icos-5-ene-8-carboxylic acid
    Show/Hide
Structure
Formula
C34H51N7O8
Molecular Weight
685.823
Canonical SMILES
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC=CC[C@H](NC1=O)C(O)=O)NC(=O)[C@@H](N)CCCCN
    Show/Hide
InChI
InChI=1S/C34H51N7O8/c1-3-20(2)28-32(46)38-25(34(48)49)11-5-4-10-24(37-29(43)23(36)9-6-7-17-35)33(47)41-18-8-12-27(41)31(45)39-26(30(44)40-28)19-21-13-15-22(42)16-14-21/h4-5,13-16,20,23-28,42H,3,6-12,17-19,35-36H2,1-2H3,(H,37,43)(H,38,46)(H,39,45)(H,40,44)(H,48,49)/t20-,23-,24-,25-,26-,27-,28-/m0/s1
    Show/Hide
InChIKey
BFWZQFFFGCRXTK-AUUFLVQBSA-N
Physicochemical Property
logP
-0.1981
Rotatable Bonds
11
Heavy Atom Count
49
Polar Areas
246.28
Hydrogen Bond Donor Count
8
Hydrogen Bond Acceptor Count
9
Complexity
49

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 145993831
ChEMBL ID
CHEMBL4294560
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02429, Neurotensin receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS