General Information of the Compound
| Compound ID |
CP0564819
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| Compound Name |
N-hydroxy-4-[(2-oxo-4-phenyl-1-prop-2-ynylquinolin-3-yl)oxymethyl]benzamide
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| Formula |
C26H20N2O4
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| Molecular Weight |
424.456
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| Canonical SMILES |
ONC(=O)c1ccc(COc2c(-c3ccccc3)c3ccccc3n(CC#C)c2=O)cc1
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| InChI |
InChI=1S/C26H20N2O4/c1-2-16-28-22-11-7-6-10-21(22)23(19-8-4-3-5-9-19)24(26(28)30)32-17-18-12-14-20(15-13-18)25(29)27-31/h1,3-15,31H,16-17H2,(H,27,29)
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| InChIKey |
ASUSNDQLHGKBEM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT01213, Histone deacetylase 6