General Information of the Compound
Compound ID
CP0564127
Compound Name
US10100018, Example 21
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Structure
Formula
C31H28FNO4
Molecular Weight
497.566
Canonical SMILES
OC(=O)c1ccc(CN(CCCCc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1
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InChI
InChI=1S/C31H28FNO4/c32-28-11-4-5-12-29(28)37-27-19-17-25(18-20-27)30(34)33(21-7-6-10-23-8-2-1-3-9-23)22-24-13-15-26(16-14-24)31(35)36/h1-5,8-9,11-20H,6-7,10,21-22H2,(H,35,36)
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InChIKey
BKRGCMOFALKWJU-UHFFFAOYSA-N
Physicochemical Property
logP
6.9815
Rotatable Bonds
11
Heavy Atom Count
37
Polar Areas
66.84
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 117903056
ChEMBL ID
CHEMBL3956413
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05651, Lysophosphatidic acid receptor 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
IC50 = 11 nM
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