General Information of the Compound
Compound ID
CP0563372
Compound Name
US8618114, 1.2.19(4).HCl
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Structure
Formula
C23H30N6O3S
Molecular Weight
470.599
Canonical SMILES
CNc1nn2c(C)c(CCC(=O)N3CCN(C)CC3)c(C)nc2c1S(=O)(=O)c1ccccc1
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InChI
InChI=1S/C23H30N6O3S/c1-16-19(10-11-20(30)28-14-12-27(4)13-15-28)17(2)29-23(25-16)21(22(24-3)26-29)33(31,32)18-8-6-5-7-9-18/h5-9H,10-15H2,1-4H3,(H,24,26)
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InChIKey
VPQBBCSZQUYDLV-UHFFFAOYSA-N
Physicochemical Property
logP
1.92724
Rotatable Bonds
6
Heavy Atom Count
33
Polar Areas
99.91
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 68261572
ChEMBL ID
CHEMBL3675193
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 6059 nM
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