General Information of the Compound
| Compound ID |
CP0562750
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| Compound Name |
N-[5-cyano-4-[[(2S)-1-methoxypropan-2-yl]amino]pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Structure |
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| Formula |
C26H32N8O4
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| Molecular Weight |
520.594
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| Canonical SMILES |
COC[C@H](C)Nc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C26H32N8O4/c1-17(16-38-3)29-21-10-23(28-12-20(21)11-27)31-26(37)34-6-4-5-18-9-19(22(15-35)30-25(18)34)13-33-8-7-32(2)14-24(33)36/h9-10,12,15,17H,4-8,13-14,16H2,1-3H3,(H2,28,29,31,37)/t17-/m0/s1
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| InChIKey |
ODGIYJISIWJCTG-KRWDZBQOSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4