General Information of the Compound
| Compound ID |
CP0562537
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| Compound Name |
N-[5-cyano-4-[(1-methylpiperidin-4-yl)methoxy]pyridin-2-yl]-6-(difluoromethyl)-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Structure |
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| Formula |
C24H26F2N6O3
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| Molecular Weight |
484.507
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| Canonical SMILES |
CN1CCC(COc2cc(NC(=O)N3CCCc4cc(C(F)F)c(C=O)nc34)ncc2C#N)CC1
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| InChI |
InChI=1S/C24H26F2N6O3/c1-31-7-4-15(5-8-31)14-35-20-10-21(28-12-17(20)11-27)30-24(34)32-6-2-3-16-9-18(22(25)26)19(13-33)29-23(16)32/h9-10,12-13,15,22H,2-8,14H2,1H3,(H,28,30,34)
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| InChIKey |
SYRXOGDLTJQMOH-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4