General Information of the Compound
Compound ID
CP0561042
Compound Name
3-[(5-tert-butyl-2-methyl-1-propylpyrrole-3-carbonyl)amino]-3-(4-tert-butylphenyl)propanoic acid
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Structure
Formula
C26H38N2O3
Molecular Weight
426.601
Canonical SMILES
CCCn1c(C)c(cc1C(C)(C)C)C(=O)NC(CC(O)=O)c1ccc(cc1)C(C)(C)C
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InChI
InChI=1S/C26H38N2O3/c1-9-14-28-17(2)20(15-22(28)26(6,7)8)24(31)27-21(16-23(29)30)18-10-12-19(13-11-18)25(3,4)5/h10-13,15,21H,9,14,16H2,1-8H3,(H,27,31)(H,29,30)
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InChIKey
FOGURFTYQYAJDN-UHFFFAOYSA-N
Physicochemical Property
logP
5.74732
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
71.33
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118727466
ChEMBL ID
CHEMBL3398414
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02999, Cytochrome P450 26A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 5190 nM
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