General Information of the Compound
Compound ID
CP0560761
Compound Name
US8772323, 115
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Structure
Formula
C17H20N4O2
Molecular Weight
312.373
Canonical SMILES
CC1CC(=O)NN=C1c1ccc2nc(oc2c1)N1CCCCC1
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InChI
InChI=1S/C17H20N4O2/c1-11-9-15(22)19-20-16(11)12-5-6-13-14(10-12)23-17(18-13)21-7-3-2-4-8-21/h5-6,10-11H,2-4,7-9H2,1H3,(H,19,22)
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InChIKey
MASHTBFHVNDAPE-UHFFFAOYSA-N
Physicochemical Property
logP
2.6782
Rotatable Bonds
2
Heavy Atom Count
23
Polar Areas
70.73
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54591024
SID: 131340831
ChEMBL ID
CHEMBL3959792
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02455, Glucose-dependent insulinotropic receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000613 MIN6 Mus musculus (Mouse)  1
1
EC50 = 1130 nM
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