General Information of the Compound
| Compound ID |
CP0560022
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| Compound Name |
N-(5-cyano-4-propan-2-yloxypyridin-2-yl)-7-formyl-6-[(2-oxopyrrolidin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Structure |
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| Formula |
C24H26N6O4
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| Molecular Weight |
462.51
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| Canonical SMILES |
CC(C)Oc1cc(NC(=O)N2CCCc3cc(CN4CCCC4=O)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C24H26N6O4/c1-15(2)34-20-10-21(26-12-18(20)11-25)28-24(33)30-8-3-5-16-9-17(19(14-31)27-23(16)30)13-29-7-4-6-22(29)32/h9-10,12,14-15H,3-8,13H2,1-2H3,(H,26,28,33)
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| InChIKey |
KLEFUSZBZSSQHZ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4