General Information of the Compound
Compound ID
CP0559164
Compound Name
N-[4-(4-aminopiperidin-1-yl)-5-(3,5-dimethylphenyl)pyridin-3-yl]benzamide
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Structure
Formula
C25H28N4O
Molecular Weight
400.526
Canonical SMILES
Cc1cc(C)cc(c1)-c1cncc(NC(=O)c2ccccc2)c1N1CCC(N)CC1
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InChI
InChI=1S/C25H28N4O/c1-17-12-18(2)14-20(13-17)22-15-27-16-23(24(22)29-10-8-21(26)9-11-29)28-25(30)19-6-4-3-5-7-19/h3-7,12-16,21H,8-11,26H2,1-2H3,(H,28,30)
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InChIKey
IWSZWDAJGJIATO-UHFFFAOYSA-N
Physicochemical Property
logP
4.54524
Rotatable Bonds
4
Heavy Atom Count
30
Polar Areas
71.25
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118057678
ChEMBL ID
CHEMBL4856084
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01505, Somatostatin receptor type 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.59 nM
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