General Information of the Compound
| Compound ID |
CP0556181
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| Compound Name |
N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-6-[[2-(dimethylamino)ethyl-methylsulfonylamino]methyl]-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Formula |
C25H33N7O6S
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| Molecular Weight |
559.649
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(CN(CCN(C)C)S(C)(=O)=O)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C25H33N7O6S/c1-30(2)8-9-31(39(4,35)36)16-19-12-18-6-5-7-32(24(18)28-21(19)17-33)25(34)29-23-13-22(38-11-10-37-3)20(14-26)15-27-23/h12-13,15,17H,5-11,16H2,1-4H3,(H,27,29,34)
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| InChIKey |
ITNZAPINLBLEPR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4