General Information of the Compound
Compound ID
CP0555127
Compound Name
7-[5-methoxy-3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)indol-1-yl]sulfonylquinoline
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Structure
Formula
C24H23N3O3S
Molecular Weight
433.533
Canonical SMILES
COc1ccc2n(cc(C3=CCN(C)CC3)c2c1)S(=O)(=O)c1ccc2cccnc2c1
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InChI
InChI=1S/C24H23N3O3S/c1-26-12-9-17(10-13-26)22-16-27(24-8-6-19(30-2)14-21(22)24)31(28,29)20-7-5-18-4-3-11-25-23(18)15-20/h3-9,11,14-16H,10,12-13H2,1-2H3
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InChIKey
PDEQDXLELCXPRY-UHFFFAOYSA-N
Physicochemical Property
logP
4.154
Rotatable Bonds
4
Heavy Atom Count
31
Polar Areas
64.43
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155557523
ChEMBL ID
CHEMBL4558840
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 82 nM
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