General Information of the Compound
Compound ID
CP0553744
Compound Name
6-(4-chlorophenyl)-3-(2-naphthalenyl)thieno[3,2-d]pyrimidin-4(3H)-one
    Show/Hide
Structure
Formula
C22H13ClN2OS
Molecular Weight
388.879
Canonical SMILES
Clc1ccc(cc1)-c1cc2ncn(-c3ccc4ccccc4c3)c(=O)c2s1
    Show/Hide
InChI
InChI=1S/C22H13ClN2OS/c23-17-8-5-15(6-9-17)20-12-19-21(27-20)22(26)25(13-24-19)18-10-7-14-3-1-2-4-16(14)11-18/h1-13H
    Show/Hide
InChIKey
XZNKOHFXNRRBKF-UHFFFAOYSA-N
Physicochemical Property
logP
5.9208
Rotatable Bonds
2
Heavy Atom Count
27
Polar Areas
34.89
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 11994273
SID: 17493394
ChEMBL ID
CHEMBL217550
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01027, Melanin-concentrating hormone receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS