General Information of the Compound
| Compound ID |
CP0553338
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| Compound Name |
N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-6-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Formula |
C26H33N7O4
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| Molecular Weight |
507.595
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(CN4C[C@H](C)N[C@H](C)C4)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C26H33N7O4/c1-17-13-32(14-18(2)29-17)15-20-9-19-5-4-6-33(25(19)30-22(20)16-34)26(35)31-24-10-23(37-8-7-36-3)21(11-27)12-28-24/h9-10,12,16-18,29H,4-8,13-15H2,1-3H3,(H,28,31,35)/t17-,18+
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| InChIKey |
IKPPEZYAZCCZLQ-HDICACEKSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4