General Information of the Compound
Compound ID
CP0553065
Compound Name
N-[4-(3-fluorophenyl)sulfonyl-2,2-dimethyl-3H-1,4-benzoxazin-8-yl]-N',N'-dimethylethane-1,2-diamine
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Structure
Formula
C20H26FN3O3S
Molecular Weight
407.511
Canonical SMILES
CN(C)CCNc1cccc2N(CC(C)(C)Oc12)S(=O)(=O)c1cccc(F)c1
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InChI
InChI=1S/C20H26FN3O3S/c1-20(2)14-24(28(25,26)16-8-5-7-15(21)13-16)18-10-6-9-17(19(18)27-20)22-11-12-23(3)4/h5-10,13,22H,11-12,14H2,1-4H3
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InChIKey
UTGUFJUEDCOAOS-UHFFFAOYSA-N
Physicochemical Property
logP
3.1655
Rotatable Bonds
6
Heavy Atom Count
28
Polar Areas
61.88
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44441242
ChEMBL ID
CHEMBL247325
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 125.89 nM
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