General Information of the Compound
Compound ID
CP0551144
Compound Name
US8952150, 53
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Structure
Formula
C29H31N9O3
Molecular Weight
553.627
Canonical SMILES
O=C(NCCOCCOCCNc1nc(Nc2ccccc2)nc(Nc2ccc3cn[nH]c3c2)n1)c1ccccc1
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InChI
InChI=1S/C29H31N9O3/c39-26(21-7-3-1-4-8-21)30-13-15-40-17-18-41-16-14-31-27-35-28(33-23-9-5-2-6-10-23)37-29(36-27)34-24-12-11-22-20-32-38-25(22)19-24/h1-12,19-20H,13-18H2,(H,30,39)(H,32,38)(H3,31,33,34,35,36,37)
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InChIKey
SFSFARVRWZAKTG-UHFFFAOYSA-N
Physicochemical Property
logP
4.1102
Rotatable Bonds
15
Heavy Atom Count
41
Polar Areas
151
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
10
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 87054970
ChEMBL ID
CHEMBL3650465
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06205, Solute carrier organic anion transporter family member 2A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 = 4040 nM
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