General Information of the Compound
| Compound ID |
CP0548059
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| Compound Name |
N-[[3-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]imidazo[1,2-a]pyridin-6-yl]methyl]-N-methyl-5-[3-methyl-5-(1,3,5-trimethylpyrazol-4-yl)pyridin-2-yl]-1,3,4-oxadiazol-2-amine
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| Formula |
C30H35N11O
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| Molecular Weight |
565.686
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| Canonical SMILES |
CN(C)CCn1cc(cn1)-c1cnc2ccc(CN(C)c3nnc(o3)-c3ncc(cc3C)-c3c(C)nn(C)c3C)cn12
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| InChI |
InChI=1S/C30H35N11O/c1-19-12-23(27-20(2)36-39(7)21(27)3)13-32-28(19)29-34-35-30(42-29)38(6)16-22-8-9-26-31-15-25(41(26)17-22)24-14-33-40(18-24)11-10-37(4)5/h8-9,12-15,17-18H,10-11,16H2,1-7H3
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| InChIKey |
YDMSMTHWQRRSNV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3
Protein ID: PT01661, Tyrosine-protein kinase receptor TYRO3
Protein ID: PT01128, Tyrosine-protein kinase receptor UFO