General Information of the Compound
| Compound ID |
CP0545312
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| Compound Name |
(4S)-3-[4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-morpholin-4-ylpyrimidin-2-yl]-4-methyl-1,3-oxazolidin-2-one
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| Structure |
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| Formula |
C18H19F3N6O3
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| Molecular Weight |
424.383
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| Canonical SMILES |
C[C@H]1COC(=O)N1c1nc(cc(n1)-c1cnc(N)cc1C(F)(F)F)N1CCOCC1
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| InChI |
InChI=1S/C18H19F3N6O3/c1-10-9-30-17(28)27(10)16-24-13(7-15(25-16)26-2-4-29-5-3-26)11-8-23-14(22)6-12(11)18(19,20)21/h6-8,10H,2-5,9H2,1H3,(H2,22,23)/t10-/m0/s1
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| InChIKey |
IHRMXTJWGFFLSO-JTQLQIEISA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT07498, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein ID: PT06232, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform