General Information of the Compound
Compound ID
CP0543753
Compound Name
1-[(3-chlorophenyl)methyl]-N-(oxolan-2-ylmethyl)pyrrolo[3,2-c]quinolin-4-amine
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Structure
Formula
C23H22ClN3O
Molecular Weight
391.902
Canonical SMILES
Clc1cccc(Cn2ccc3c(NCC4CCCO4)nc4ccccc4c23)c1
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InChI
InChI=1S/C23H22ClN3O/c24-17-6-3-5-16(13-17)15-27-11-10-20-22(27)19-8-1-2-9-21(19)26-23(20)25-14-18-7-4-12-28-18/h1-3,5-6,8-11,13,18H,4,7,12,14-15H2,(H,25,26)
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InChIKey
SBQISXWGDOECAN-UHFFFAOYSA-N
Physicochemical Property
logP
5.4821
Rotatable Bonds
5
Heavy Atom Count
28
Polar Areas
39.08
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168288135
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 696 nM
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