General Information of the Compound
Compound ID
CP0542413
Compound Name
2-(2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-1H-indol-4-yl)-N-ethyl-N-methylethanamine
    Show/Hide
Structure
Formula
C23H25ClN4O
Molecular Weight
408.933
Canonical SMILES
CCN(C)CCc1cccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1
    Show/Hide
InChI
InChI=1S/C23H25ClN4O/c1-3-28(2)14-13-17-5-4-6-20-19(17)15-21(25-20)23-26-22(27-29-23)12-9-16-7-10-18(24)11-8-16/h4-8,10-11,15,25H,3,9,12-14H2,1-2H3
    Show/Hide
InChIKey
MRJAJLNTQWENGC-UHFFFAOYSA-N
Physicochemical Property
logP
5.1507
Rotatable Bonds
8
Heavy Atom Count
29
Polar Areas
57.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 136043779
ChEMBL ID
CHEMBL210292
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS