General Information of the Compound
Compound ID
CP0541690
Compound Name
N,N-dimethyl-2-[2-[3-[2-(4-methylphenyl)ethyl]-1,2,4-oxadiazol-5-yl]-1H-indol-4-yl]ethanamine
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Structure
Formula
C23H26N4O
Molecular Weight
374.488
Canonical SMILES
CN(C)CCc1cccc2[nH]c(cc12)-c1nc(CCc2ccc(C)cc2)no1
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InChI
InChI=1S/C23H26N4O/c1-16-7-9-17(10-8-16)11-12-22-25-23(28-26-22)21-15-19-18(13-14-27(2)3)5-4-6-20(19)24-21/h4-10,15,24H,11-14H2,1-3H3
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InChIKey
BKACHYMVJKEMDI-UHFFFAOYSA-N
Physicochemical Property
logP
4.41562
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
57.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 136043796
ChEMBL ID
CHEMBL211310
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 230 nM
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